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Jimena García Selected Research

Chlorpyrifos (Lorsban)

6/2021Chlorpyrifos induces cell proliferation in MCF-7 and MDA-MB-231 cells, through cholinergic and Wnt/β-catenin signaling disruption, AChE-R upregulation and oxidative stress generation after single and repeated treatment.
1/2021Aryl Hydrocarbon Receptor Activation Produces Heat Shock Protein 90 and 70 Overexpression, Prostaglandin E2/Wnt/β-Catenin Signaling Disruption, and Cell Proliferation in MCF-7 and MDA-MB-231 Cells after 24 h and 14 Days of Chlorpyrifos Treatment.
7/2020Chlorpyrifos-induced cell proliferation in human breast cancer cell lines differentially mediated by estrogen and aryl hydrocarbon receptors and KIAA1363 enzyme after 24 h and 14 days exposure.
1/2018SN56 neuronal cell death after 24 h and 14 days chlorpyrifos exposure through glutamate transmission dysfunction, increase of GSK-3β enzyme, β-amyloid and tau protein levels.
1/2016SN56 basal forebrain cholinergic neuronal loss after acute and long-term chlorpyrifos exposure through oxidative stress generation; P75(NTR) and α7-nAChRs alterations mediated partially by AChE variants disruption.
10/2015Acute and long-term exposure to chlorpyrifos induces cell death of basal forebrain cholinergic neurons through AChE variants alteration.

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Jimena García Research Topics

Disease

11Cognitive Dysfunction
02/2022 - 10/2015
3Breast Neoplasms (Breast Cancer)
06/2021 - 07/2020
2Neoplasms (Cancer)
06/2021 - 07/2020
1Poisoning
07/2019
1Alzheimer Disease (Alzheimer's Disease)
10/2015
1Neurodegenerative Diseases (Neurodegenerative Disease)
11/2014
1Necrosis
03/2014

Drug/Important Bio-Agent (IBA)

6Chlorpyrifos (Lorsban)IBA
06/2021 - 10/2015
4CadmiumIBA
02/2022 - 11/2014
4Cholinergic Agents (Cholinergics)IBA
10/2020 - 01/2016
4OrganophosphatesIBA
07/2020 - 10/2015
3Disinfectants (Biocides)IBA
06/2021 - 07/2020
3InsecticidesIBA
01/2018 - 10/2015
2ManganeseIBA
10/2020 - 03/2019
2ParaquatIBA
10/2020 - 02/2020
2EnzymesIBA
07/2020 - 01/2018
1bisphenol AIBA
11/2021
1PlasticizersIBA
11/2021
1Reactive Oxygen Species (Oxygen Radicals)IBA
06/2021
1AcetylcholinesteraseIBA
06/2021
1Acetylcholine (Acetylcholine Chloride)FDA Link
06/2021
1CateninsIBA
06/2021
1Brain-Derived Neurotrophic Factor (BDNF)IBA
10/2020
1Dinoprostone (PGE2)FDA Link
10/2020
1Amyloid beta-PeptidesIBA
10/2020
1N- (2- cyclohexyloxy- 4- nitrophenyl)methanesulfonamideIBA
10/2020
1Proteins (Proteins, Gene)FDA Link
10/2020
1Acetylcysteine (Siran)FDA LinkGeneric
10/2020
1Estrogens (Estrogen)FDA Link
07/2020
1Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA
07/2020
1Aromatic HydrocarbonsIBA
07/2020
1HerbicidesIBA
02/2020
1amitraz (Taktic)IBA
07/2019
1tau Proteins (tau Protein)IBA
01/2018
1Adenosine Triphosphatases (ATPase)IBA
03/2014